Электрический орган

Для дальнейшего развития исследований ацетилхолина и механизмов его высвобождения следовало подобрать ткань более удобную для экспериментов, чем мозг грызунов. В мозговой ткани лишь малая часть нервных окончаний относится к холинергическим. Более гомогенный материал в принципе можно было бы получить из областей контакта между нервами и мышечными клетками, так как все мотонейроны имеют холинер- гические синапсы. Однако от всей массы мышечного волокна нервные окончания в таких контактах составляют очень небольшую долю.

И тут оказалось, что прекрасным источником материала для изучения холинергической синаптической передачи может быть электрический скат Torpedo. У каждой особи имеется па

ра специализированных органов, называемых электрическими, способных генерировать кратковременные электрические разряды, которыми рыба пользуется для парализации добычи и для зашиты.

Электрический орган хорошо подходит для экспериментов с ацетилхо- лином, поскольку в нем сосредоточено огромное количество синапсов, которые, как показали в 1940 г. А. Фес- сард, В. Фельдберг и Д. Нахманзон, работавшие на морской биологической станции в Аркашоне (Франция), являются холинергическими. Электрический орган, по существу, представляет собой специфически измененнную нервно-мышечную систему, и механизм передачи нервного импульса в нем во многом такой же, как в обычной системе. К примеру, в электрическом органе тоже регистрируются миниатюрные и субминцатюрные потенциалы концевой пластинки. Вместе с тем экспериментальные препараты, полученные из электрического органа, не содержат ни усложняющих исследование сократительных структур, характерных для мышечных клеток, ни сложных нейронных цепей и гетерогенного набора нейромедиаторов, которые свойственны центральной нервной системе.

 

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  737. The refreshing Zune browser is surprisingly very good, but not as good as the iPod’s. It will work perfectly, however isn’t as fast as Safari, and consists of a clunkier interface. If you from time to time method upon making use of the internet browser that’s not an issue, yet if you’re building in direction of study the world-wide-web alot in opposition to your PMP then the iPod’s much larger exhibit and much better browser may be crucial.

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  748. If you are nonetheless on the fence: seize your favored earphones, head down in the direction of a Ideal Order and check with towards plug them into a Zune then an iPod and watch which one sounds superior towards on your own, and which interface makes oneself smile much more. Then you are going to notice which is right for yourself.

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  754. Apple previously incorporates Rhapsody as an application, which is a superb start off, but it is currently hampered via the incapacity toward shop locally on your iPod, and consists of a dismal 64kbps little bit rate. If this improvements, then it will rather negate this comfort for the Zune, nevertheless the Ten new music per thirty day period will even now be a big as well as within Zune Pass’ like.

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